Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 11;30(1):353–370. doi: 10.1093/cercor/bhz092

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

PMC Copyright notice

CVS results in a comparable degree of adrenocortical hyperactivity in both sexes. (A) Timelines of the first experiment, displaying individual timelines for each cohort (1 and 2). (B, C) Both groups of rats showed decreases in body weight gain (B) and adrenal hypertrophy (C) through the course of the 14-day CVS period. (D) Graph depicting mean ± SEM plasma CORT levels at AM and PM sampling of CORT as a function of sex and treatment group. Measurements were taken in the same rats prior (left) to and following (right) CVS. CVS resulted in significantly increased PM levels of CORT (^*, P < 0.05), regardless of sex. (E) Graph showing changes in the daily mean values of CORT levels pre- and post-CVS as a function of sex and treatment group. CVS increased levels of CORT in both sexes (^*, P < 0.05), whereas levels of CORT were higher in female rats (†, P < 0.05). N = 10–11/group.