Table 1.
Differential, significant functional connections of the two core distinct vmPFC clusters identified in the functional resting-state data
Contrast | Region of Activation | Cluster extent (voxels) | Max z value | P value (FWE corrected) | Peak MNI Coordinate | ||
---|---|---|---|---|---|---|---|
X | Y | Z | |||||
Purple (Dorsal) Cluster > Red (Ventral) Cluster | Bilateral dmPFC, ACC, IFG, precuneus, PCC, thalamus & L pMTL, sTP & MTG | 9207 | Inf | >.001 | −3 | 57 | 15 |
L AG | 703 | Inf | >.001 | −51 | −60 | 30 | |
Cerebellum | 671 | Inf | >.001 | 27 | −81 | −36 | |
R AG | 366 | Inf | >.001 | 54 | −57 | 30 | |
R MTG | 632 | 6.77 | >.001 | 63 | −12 | −15 | |
Red (Ventral) Cluster > Purple (Dorsal) Cluster | Bilateral OFC & aPHG | 2435 | Inf | >.001 | −12 | 36 | −21 |
L vATL & pITC | 404 | Inf | >.001 | −51 | −39 | −27 | |
R vATL | 180 | 6.73 | .002 | 33 | −27 | −30 |
Clusters significant at 0.05 after FWE correction. L = left, R = right, a = anterior, p = posterior, dmPFC = dorsomedial prefrontal cortex, IFG = inferior frontal gyrus, PCC = posterior cingulate cortex, MTL = medial temporal lobe, sTP = superior temporal pole, MTG = middle temporal gyrus, AG = angular gyrus, OFC = orbitofrontal cortex, vATL = ventral anterior temporal lobe, PHG = parahippocampal gyrus and ITC = inferior temporal cortex.