Figure 3.

Voxel-based morphometry map of increased white matter clusters in HF piglets compared to CON. Voxel-based morphometry revealed HF fed piglets have more white matter in several key regions compared to CON fed piglets regardless of birth weight. These areas were the next to the lateral ventricle (periventricular white matter), the internal capsule, the left and right cortices, the midbrain, and the hypothalamus. Each image is a 1 mm axial slice composite of all piglet brains. The color bar represents the pseudo-T statistic indicating level of significance, with red indicating highest statistical difference between voxels. Values are 6–8 replicate pigs with MRI data collected at 26–29 days of age as described in Table 3. AGA, appropriate for gestational age; SGA, small for gestational age; CON, control; HF, hydrolyzed fat.