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. 2020 Feb 12;11:166. doi: 10.3389/fmicb.2020.00166

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Copyright © 2020 Almebairik, Zamudio, Ironside, Joshi, Ralph, Roberts, Gould, Morrissey, Hijazi and Oggioni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic map of the ACME-I in S. epidermidis. comparative organization of ACME-I composite island in the seven ST48, ST54, ST35 S. epidermidis isolates. The size of each ACME composite island is indicated after the strain names. Four distinct ACME-I composite island were defined according to the additional modules in these elements (A–D). Each gene or group of genes of interest is shaded in color; arc and opp3 operons (red), speG (light purple), copB (brown), mco (light yellow), copL (ornage), ars operon (dark purple), mecA, mecR1, IS431, IS1272, and ccrAB2 (dark blue). The direct repeat (DR) sequences DRA, DR-B, DR-C, and the new DR are indicated.