Table 3:

Pregnancy and infant health outcomes according to maternal CMV DNA status

	N	Detectable CMV DNA, n = 51	No detectable CMV DNA, n= 299	Unadjusted odds ratio (OR) of having the outcome of interest, in association with detectable CMV DNA (95%confidence interval [CI])	P	Adjusted odds ratio (OR) of having the outcome of interest, in association with detectable CMV DNA (95% confidence interval [CI])	P
Pregnancy Outcomes
Stillbirth	298	0/42 (0)	0/256 (0)	-	-	-	-
Birth defect	298	3/42 (7.1)	2/256 (0.8)	9.8 (1.6 -60.3)	0.01	*	-
Small for gestational age (<10th percentile)	298	14/42 (33.3)	61/256 (23.8)	1.6 (0.79 – 3.2)	0.2	1.5 (0.7 – 2.9) a	0.3
Very small for gestational age (<3rd percentile)	298	10/42 (23.8)	42/256 (16.4)	1.6 (0.7 – 3.5)	0.2	-	-
Preterm delivery (<37 weeks gestation)	298	9/42 (21.4)	27/256 (10.5)	2.3 (1.0- 5.3)	0.06	*	-
Very preterm delivery (≤32 weeks gestation)	298	1/39 (2.3)	3/256(1.2)	2.2 (0.22 – 21.4)	0.5	-	-
Composite adverse birth outcome**	298	19/42 (45.2)	74/256 (28.9)	2.0 (1.04- 3.95)	0.04	1.9 (0.96 – 3.8) b	0.06
Infant Health Outcomes
Hospitalization	298	7/42 (16.7)	47/256 (18.3)	0.89 (0.4 -2.1)	0.8	-	-
Infant mortality	298	0/42 (0)	1/256 (0.4)	-	-	-	-
Composite adverse infant health outcome***	298	7/42 (16.7)	48/256 (18.8)	0.9 (0.4 - 2.1)	0.7	0.9 (0.4 – 2.1) c	0.7

CI, confidence interval; CMV, cytomegalovirus; DNA, deoxyribonucleic acid; OR, odds ratio

^*Adjusted odds ratios are unavailable as co-variates did not meet the criteria for inclusion in the multivariate model

^**Defined as presence of one or more of the following outcomes: stillbirth, birth defect, small for gestational age or preterm delivery

^***Defined as hospitalization and/or death by 24 months

^aAdjusted for type of ARV prophylaxis (ZDV or 3-drug ART) received during current pregnancy

^bAdjusted for baseline CD4 count, and type of ARV prophylaxis (ZDV or 3-drug ART) received during current pregnancy

^cAdjusted for baseline CD4 count