Table 1. Hinges predicted for PACKMAN with alpha = 2.8.

Hinge 6 in NS5 has a p-value > 0.05 however, this hinge has been noted as an important flexible region in the literature.

Protein Name	PDB ID	Hinge	Position	p-value
NS5	5M2Z	1	H-307 - N-323	0
		2	T-337 - P-367	0
		3	S-450 - R-483	0
		4	A568 - D-599	0
		5	R-601 - V-606	0
		6	R-741 - W-748	0.097
NS2B-NS3 Pro	5H4I	1	G-21 - V-25	0.0
		2	Q-96 - V-100	0.046
		3	G-133 - I-139	0.001
		4	V-146 - G-151	0.001
NS3-HEL	6MH3	1	F-289 - A-297	0
		2	D-425 - I-434	0
		3	V-440 - R-456	0
		4	Y-473 - L-494	0
		5	L-507 - A-517	0.008