KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| Goat anti-GFP | Abcam | ab6658, RRID: AB_305631 |
| Rabbit anti-HOPX | Santa Cruz Biotechnology | sc-30216, RRID: AB_2120833 |
| Mouse anti-PTPRZ1 | Santa Cruz Biotechnology | sc-33664, RRID: AB_2253176 |
| Mouse anti-SOX2 | Santa Cruz Biotechnology | sc-365823, RRID: AB_10842165 |
| Rabbit anti-PTPRZ1 | Atlas Antibodies | HPA015103, RRID: AB_1855946 |
| Rabbit anti-PDGFRA | Cell Signaling | 3174S, RRID: AB_2162345 |
| Rabbit anti-GLAST | Abcam | ab416, RRID: AB_304334 |
| Rabbit anti-OLIG2 | Millipore | AB9610, RRID: AB_570666 |
| Mouse anti-SATB2 | Abcam | ab51502: AB_882445 |
| Mouse anti-CD31 | Agilent | GA610, RRID: AB_2114471 |
| Mouse anti-Ki67 | Dako | M724001, RRID: AB_2631211 |
| Bacterial and Virus Strains | ||
| CMV-adeno-GFP virus | Vector Biolabs | 1060 |
| Chemicals, Peptides, and Recombinant Proteins | ||
| BDNF, 20ng/mL | Millipore Sigma | SRP3014-10 |
| 3-Benzyl-5-((2-nitrophenoxy)methyl)-dihydrofuran-2(3H)-one (3BDO) (Peng et al., 2014), 60uM | Millipore Sigma | SML1687 |
| Rock Inhibitor Y-27632 | Tocris | 1254 |
| IWR-1-endo | Cayman Chemical | 13659 |
| SB431542 | Tocris | 1614 |
| Critical Commercial Assays | ||
| 10X Chromium v2 | 10X Genomics | PN-120237 |
| Deposited Data | ||
| Single-Cell RNA-sequencing | PRJNA579593 | N/A |
| Experimental Models: Cell Lines | ||
| DBTRGFL PDX Line | Brain Tumor Research Center UCSF | N/A |
| Experimental Models: Organisms/Strains | ||
| CD1 Mice | Jackson Laboratory | 003814 |
| Oligonucleotides | ||
| PTPRZ1 qPCR primer F1 | ATC CTG GCA GCA GGT GAC TCA G | N/A |
| PTPRZ1 qPCR primer R1 | CCT CAG CTA GAC CAA TAC GAG AC | N/A |
| Software and Algorithms | ||
| Seurat v2 | Publicly Available | N/A |