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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Anesthesiology. 2020 Mar;132(3):491–503. doi: 10.1097/ALN.0000000000003065

Figure 5.

Figure 5.

Pain tolerance in the Cold Pressor Test at baseline and the three testing periods during pharmacokinetically tailored IV infusion of fentanyl on pre- (closed symbol) and post- (open symbol) treatment days in the placebo (blue squares) and St. John’s wort (red circles) groups (n = 8 in each). Results are the mean ± SD.