Table 4.
Univariate and multivariate analyses of clinicopathological characteristics and C2orf48 with overall survival for liver cancer patients in TCGA-LIHC cohort.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Sex (Male vs. Female) | 0.817 (0.603–1.107) | 0.192 | ||
| Age, years (≥median vs. <median) | 1.402 (1.033–1.903) | 0.03* | 1.331 (0.973–1.822) | 0.074 |
| Neoplasm status (tumor free vs. with tumor) | 1.745 (1.277–2.385) | <0.001*** | 1.59 (1.154–2.19) | 0.005** |
| Risk factors (alcohol consumption vs. non-alcohol consumption) | 1.06 (0.759–1.48) | 0.734 | ||
| Histologic grade (G1+G2 vs. G3+G4) | 1.316 (0.853–2.03) | 0.215 | ||
| Clinical stage (stage I+II vs. stage III+IV) | 1.566 (1.151–2.131) | 0.004** | 1.328 (0.965–1.828) | 0.032* |
| C2orf48 (≥median vs. <median) | 1.406 (1.039–1.902) | 0.027* | 1.298 (0.936–1.8) | 0.041* |
HR – hazard ratio; CI – confidence interval.
*
p value<0.05;
**
p value<0.01;
***
p value<0.001.