Table 2. Relationships of monocytes subsets with anthropometric, and metabolic features in basal state.
| Dependent variable | Regressors | β±S.E. | T | p-level |
|---|---|---|---|---|
| Non-classical monocytes (NCM; CD14-CD16++) Adjusted R2 = 0.135 | ||||
| Intercept | 4.97 | <0.000002 | ||
| HOMA-IR | 0.33±0.08 | 4.26 | <0.000037 | |
| Acylated-ghrelin | -0.16±0.08 | 1.98 | <0.04 | |
| Intermediate monocytes (IM; CD14+CD16+) Adjusted R2 = 0.127 | ||||
| Intercept | 2.62 | <0.0098 | ||
| Caloric intake | 0.17±0.08 | 2.00 | <0.047 | |
| CD16+/CD16- ratio Adjusted R2 = 0.080 | ||||
| Intercept | 0.27 | 0.78 | ||
| BMI | 0.35±0.09 | 3.73 | <0.00028 | |
| Leptin | -0.19±0.09 | -2.06 | <0.041 | |
| ILC2s Adjusted R2 = 0.098 | ||||
| Intercept | 4.06 | <0.000082 | ||
| Caloric intake | -0.24±0.08 | -2.87 | <0.0046 | |
| HDL-C | 0.16±0.08 | 1.97 | <0.05 | |
| β2AR expression on NCM Adjusted R2 = 0.119 | ||||
| Intercept | -2.37 | <0.019 | ||
| Mean arterial tension | 0.28±0.08 | 3.35 | <0.001 | |
| Leptin | 0.22±0.08 | 2.54 | <0.012 | |
| HDL-C | 0.21±0.08 | 2.50 | <0.013 | |
| HOMA-IR | -0.18±0.09 | -2.01 | <0.045 | |
| β2AR expression on IM Adjusted R2 = 0.322 | ||||
| Intercept | -0.70 | 0.48 | ||
| HDL-C | 0.42±0.08 | 5.13 | <0.000001 | |
| BMI | 0.41±0.09 | 4.52 | <0.00001 | |
| REE | -0.25±0.08 | -2.92 | <0.004 | |
| β2AR expression on CM Adjusted R2 = 0.360 | ||||
| Intercept | -1.38 | <0.016 | ||
| HDL-C | 0.30±0.08 | 3.45 | <0.0007 | |
| BMI | 0.24±0.09 | 2.63 | <0.009 | |
| Age | 0.21±0.08 | 2.45 | <0.015 | |
| Non-HDL-C | -0.17±0.08 | -2.08 | <0.039 | |
The associations were evaluated by multiple regression. p<0.05 was considered statistically significant.
BMI, body mass index; EE, energy expenditure; β2AR, beta-2 adrenergic receptor; NCM, non-classical monocytes (CD14-CD16++); IM, intermediate monocytes (CD14+CD16+); CM, classical monocytes (CD14+CD16+); ILC2s, group 2 innate lymphoid cells.