Table 1.
Average protein length, total and relative densities of conserved noncoding elements (CNE) and transposable elements (TE), and transcript numbers per gene within the human genome broken down according to gene size. Note that protein length and transcript numbers increase consistently with gene size, although intron length is primarily responsible for overall gene size. CNE density increases with gene size but is somewhat variable and TE density peaks between the 10,000bp-200,000bp then modestly decreases with gene size. The vast majority of genes in the human genome (91%) fall under 150,000bp in size. (See Casanova et al., 2019, Supplementary Material 2 for full published data.)
Gene Length (bp) | N (genes) | Protein Length (aa) | Total CNE (CNE/gene) | CNE Density (CNE/gene normalized by gene length) | Total TE (TE/gene) | TE Density (TE/gene normalized by gene length) | Number of Transcripts (per gene) |
---|---|---|---|---|---|---|---|
147–10,000 | 5,802 | 318 | 39 | 6.4 | 4 | 0.7 | 3.2 |
10,001–25,000 | 4,311 | 465 | 183 | 11.0 | 26 | 1.5 | 4.0 |
25,001–50,000 | 3,395 | 603 | 411 | 11.5 | 60 | 1.7 | 4.4 |
50,001–100,000 | 2,631 | 751 | 796 | 11.4 | 117 | 1.7 | 4.5 |
100,001–150,000 | 1,155 | 964 | 1,349 | 11.1 | 192 | 1.6 | 4.8 |
150,001–200,000 | 562 | 1,078 | 1,935 | 11.2 | 263 | 1.5 | 4.8 |
200,001–400,000 | 773 | 1,146 | 3,259 | 11.7 | 399 | 1.4 | 5.2 |
400,001–600,000 | 228 | 1,212 | 5,661 | 11.8 | 646 | 1.3 | 5.5 |
600,001–800,000 | 70 | 1,297 | 8,062 | 11.7 | 929 | 1.3 | 5.7 |
800,001–1,000,000 | 41 | 1,257 | 11,250 | 12.5 | 1,160 | 1.3 | 5.8 |
1,000,001–1,200,000 | 19 | 894 | 11,923 | 10.5 | 1,421 | 1.3 | 6.1 |
1,200,001–1,400,000 | 11 | 999 | 16,130 | 12.7 | 1,732 | 1.4 | 5.8 |
1,400,001+ | 17 | 1,846 | 24,229 | 13.0 | 2,325 | 1.3 | 6.6 |