表 4. EC-SOD/ALDH2基因型和饮酒状况与口腔鳞状细胞癌易患性的协同分析.
Tab 4 Combined analysis of genotypes of EC-SOD/ALDH2 and drinking status on oral squamous cell carcinoma susceptibility
| 联合基因型 |
饮酒状况 | 病例组 | 对照组 | OR值 | 95%CI | P值 | |
| EC-SOD | ALDH2 | （n/%） | （n/%） | ||||
| C/C | G/G | - | 55/7.33 | 125/16.67 | 1.00 | ||
| C/C | G/G | + | 117/15.60 | 185/24.67 | 1.44 | 0.82~2.58 | >0.05 |
| C/C | non-G/G | - | 191/25.47 | 272/36.27 | 1.60 | 1.27~2.97 | >0.05 |
| C/C | non-G/G | + | 100/13.33 | 10/1.33 | 22.73 | 11.41~32.83 | < 0.01 |
| C/G | G/G | - | 10/1.33 | 20/2.67 | 1.14 | 0.87~1.75 | >0.05 |
| C/G | G/G | + | 47/6.27 | 87/11.60 | 1.23 | 0.72~2.46 | >0.05 |
| C/G | non-G/G | - | 10/1.33 | 31/4.13 | 0.73 | 0.52~1.29 | >0.05 |
| C/G | non-G/G | + | 220/29.33 | 20/2.67 | 25.00 | 11.62~34.94 | < 0.01 |
| C/C | G/G | DI≤3 000 | 25/3.33 | 135/18.00 | 1.00 | ||
| C/C | G/G | DI>3 000 | 92/12.27 | 50/6.67 | 9.94 | 5.95~12.40 | < 0.01 |
| C/C | non-G/G | DI≤3 000 | 65/8.67 | 7/0.93 | 50.14 | 28.03~68.92 | < 0.01 |
| C/C | non-G/G | DI>3 000 | 35/4.67 | 3/0.40 | 63.00 | 58.36~117.26 | < 0.01 |
| C/G | G/G | DI≤3 000 | 22/2.93 | 45/6.00 | 2.64 | 1.94~4.59 | >0.05 |
| C/G | G/G | DI>3 000 | 25/3.33 | 42/5.60 | 3.21 | 2.43~7.51 | >0.05 |
| C/G | non-G/G | DI≤3 000 | 7/0.93 | 15/2.00 | 2.52 | 2.18~4.92 | >0.05 |
| C/G | non-G/G | DI>3 000 | 213/28.40 | 5/0.67 | 230.04 | 159.07~326.48 | < 0.01 |