Fig 6. Analysis of known and predicted protein-protein interaction networks at 24 HPLT.

Modulated proteins (Fold change >0.5 and <-0.5) were used as input for STRING analysis to reveal known and predicted protein-protein interaction networks. Proteins are indicated by nodes labeled with the encoding gene symbol. Additional cluster analysis was used to colour the nodes of the interaction networks (k-means = 2). The analysis showed the modulation of a network of interaction that was mainly composed of proteins related to cellular cytoskeleton (red cluster).