Table 1.
Characteristics of the study population.
| young male (n = 221) | young female (n = 244) | old male (n = 761) | old female (n = 747) | P | |
|---|---|---|---|---|---|
| Age (years) | 29.2 (28.8; 29.6)a | 28.6 (28.2; 29.0)a | 68.9 (68.7; 69.2)b | 68.3 (68.0; 68.5)c | <0.001 |
| Weight (kg)a | 77.9 (76.1; 79.7)a | 64.5 (62.8; 66.2)b | 84.0 (83.1; 84.9)c | 70.1 (69.2; 71.0)d | <0.001 |
| Height (cm) | 180.8 (179.9; 181.7)a | 168.5 (167.7; 169.3)b | 175.6 (175.1; 176.0)c | 162.9 (162.5; 163.3)d | <0.001 |
| BMI (kg/m2)a | 23.8 (23.3; 24.3)a | 22.7 (22.1; 23.2)b | 27.2 (27.0; 27.5)c | 26.5 (26.1; 26.8)d | <0.001 |
| BMI-Groups | |||||
| < 18.5 | 4.1 (9) | 9.0 (22) | 0.0 (0) | 0.7 (5) | |
| 18.5–24.9 | 64.3 (142) | 70.9 (173) | 28.2 (214) | 43.4 (324) | <0.001 |
| 25.0–29.9 | 27.1 (60) | 13.5 (33) | 54.9 (417) | 35.5 (265) | |
| ≥ 30.0 | 4.5 (10) | 6.6 (16) | 17.0 (129) | 20.5 (153) | |
| Current smoker | 34.8 (77) | 27.5 (67) | 10.4 (79) | 8.2 (61) | <0.001 |
| Cholesterol (μmol/L) | 4460 (4356; 4563)a | 4698 (4588; 4808)b | 5284 (5214; 5355)c | 5866 (5794; 5938)d | <0.001 |
| eGFR | 117.9 (115.8; 120.0)a | 113.9 (112.0; 115.8)b | 70.2 (69.4; 71.1)c | 68.4 (37.7; 69.3)d | <0.001 |
| MMSE | n.a. | n.a. | 28.31 ± 1.40 | 28.78 ± 1.60 | <0.001 |
| Medication | n.a. | n.a. | 2.66 ± 2.41 | 2.93 ± 2.34 | 0.038 |
a
Weight/BMI was missing for n = 1 old male. GLM with Bonferroni post-hoc test for continuous variables, Chi-squared test for categorical variables; n.a.: not available; continuous variables are expressed as mean (95% CI) or mean ± SD and categorical variables are expressed as % (n). Cholesterol (n = 1965), MMSE (n = 1409) and Medication (n = 1235).