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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Nat Genet. 2020 Jan 20;52(2):138–145. doi: 10.1038/s41588-019-0568-7

Extended Data Fig. 3:

Extended Data Fig. 3:

BCL11A protein expression is regulated via translation by polysome-associated LIN28B

a, Western blots for BCL11A in the input and flow-through (FT) fractions of the immunoprecipitate in newborn (left) and adult (right) erythroid cells (2 independent experiments). b, Western blots for BCL11A and GATA1 in the total immunoprecipitate (IP) in newborn (left) and adult (right) erythroid cells after L-azidohomoalanine (L-AHA) labeling for 6 hours at day 7 of differentiation, followed by immunoprecipitation with BCL11A and GATA1 antibodies. c, Quantification of adult-BCL11A (blue) and newborn-BCL11A (purple) mRNAs across the different sucrose gradient fractions are shown as a percentage of the gradient. Cells were differentiated until day 7. Blots have been cropped and the corresponding full blots are available in the Source Data files.