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. Author manuscript; available in PMC: 2020 Feb 22.
Published in final edited form as: Prostate Cancer Prostatic Dis. 2019 Aug 22;23(1):127–135. doi: 10.1038/s41391-019-0168-8

Figure 3:

Figure 3:

Dietary ω−3 fatty acids (as compared to ω−6) decreased tumor growth in established CRPC and decreased expression of VEGF and MMP-9 in tumor infiltrating M2-like macrophages. (A) Tumor growth. Pre-castration tumor volume not shown (n=14 ω−3 diet, n=14 ω−6 diet). Tumor volume over time was compared between groups (Fig 1A and Fig 3A) using Generalized Estimating Equations (GEE) models. (B) Tumor weight (n=14 ω−3 diet, n=14 ω−6 diet). (C) Gene expression in M2-like macrophages isolated from tumor tissue (n=11 ω−3 diet, n=10 ω−6 diet). Data are means±SEM; *p<0.05, **p<0.01, ***p<0.003.