Table 1.
Characteristics of patients with and without bacteremia.
| Variables | Number of patients (n = 111) | Bacteremia |
P-value | |
|---|---|---|---|---|
| Present (n = 46) | Absent (n = 65) | |||
| Age, years | ||||
| Median (IQR) | 7.9 (4.4 - 13) | 9.75 (2.7-14.8) | 7.4 (4.4-11.4) | 0.284 |
| Range | 0.5 – 17.9 | 0.5 – 17.9 | 0.7 – 17.1 | |
| Gender, male, n (%) | 65 (58.6) | 23 (50) | 42 (64.6) | 0.124 |
| Graft source, n (%) | ||||
| Bone marrow | 56 (50.5) | 23 (50) | 33 (50.8) | 0.936 |
| Peripheral blood | 53 (47.8) | 21 (45.7) | 32 (49.2) | 0.710 |
| Cord blood | 4 (3.6) | 2 (4.4) | 2 (3.1) | 0.723 |
| Diagnosis, n (%) | 0.245 | |||
| ALL | 43 (38.7) | 21 (45.6) | 22 (33.8) | |
| AML | 17 (15.3) | 6 (13) | 11 (16.9) | |
| Solid tumor | 15 (13.5) | 3 (6.5) | 12 (18.5) | |
| Aplastic Anaemia | 12 (10.8) | 5 (10.8) | 7 (10.8) | |
| PID | 9 (8.1) | 3 (6.5) | 6 (9.2) | |
| MDS | 6 (5.4) | 5 (10.9) | 1 (1.5) | |
| Lymphoma | 5 (4.5) | 2 (4.3) | 3 (4.6) | |
| others | 4 (3.6) | 1 (2.2) | 3 (4.6) | |
| Allogeneic stem cell transplant, n (%) | 92 (83) | 42 (91) | 50 (77) | 0.048 |
| Autologous stem cell transplant, n(%) | 19 (17) | 4 (9) | 15 (23) | |
| Type of allogeneic donor, n = 92(%) | 0.165 | |||
| Haploidentical | 69 (75) | 35 (83.3) | 34 (68) | |
| Identical sibling | 19 (20.6) | 5 (11.9) | 14 (28) | |
| Matched unrelated donor | 4 (4.35) | 2 (4.8) | 2 (4) | |
| Status at transplantation, n = 60 (leukemias) | 0.877 | |||
| First complete remission | 22 (36.7) | 9 (33) | 13 (39.4) | |
| Second or more complete remission | 30 (50) | 14 (51.8) | 16 (48.5) | |
| Active disease | 8 (13) | 4 (14.8) | 4 (12) | |
| Mucositis | 77 (69.4) | 35(76) | 42(64.6) | 0.374 |
| Moderate/severe | 40 (51.9) | 17(48.5) | 23(54.7) | 0.374 |
| aGvHD I-IV, n = 91 (%) | 53(58.2) | 27 (29.7) | 26(28.5) | 0.299 |
aGvHD, acute graft-versus-host disease; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; IQR, interquartile range; MDS, myelodysplastic syndrome; PID, primary immunodeficiency diseases.