Skip to main content
. 2020 Jan 22;34:112–123. doi: 10.1016/j.molmet.2020.01.008

Figure 4.

Figure 4

Myeloid cell-specific iRhom2 deletion downregulates insulin resistance and inflammation in obese mice. (A) Body weight was examined before and after the feeding period, n = 15. (B) Body composition, n = 10. (C) Glucose and (D) insulin tolerance test, n = 15. Western blotting bands of the expression of (E) insulin signaling from iWAT and (F) inflammation signaling of F4/80+ macrophages in iWAT. mRNA expression of the genes responsible for (G) lipid metabolism and (H) inflammatory cytokines and chemokines in HFD-fed WTBM→WT/HFD and KOBM→WT/HFD mice, n = 6. The data are expressed as mean ± SEM, *p < 0.05.