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. 2020 Feb 13;11:17. doi: 10.3389/fphar.2020.00017

Figure 3.

Figure 3

miR-3568 mimic regulated the MAPKs, AKT, and STAT3 signaling in simulated I/R-induced H9C2 cardiomyocytes. H9C2 cardiomyocytes were transfected with miR-3568 mimic or inhibitor and then simulated I/R for 3 h. (A–C) The expression of p-ERK1/2, ERK1/2, p-JNK1/2, JNK1/2, p-p38, p38, p-AKT, AKT, p-STAT3, and STAT3 was measured by western blot (n = 3). Statistical analyses were carried out using two-way analysis of variance followed by Bonferroni post-test. ***P < 0.001 compared with control. ##P < 0.01, ###P < 0.001 compared with I/R + NC.