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. 2020 Jan 16;180(1):73–86. doi: 10.1007/s10549-020-05532-6

Table 2.

MRPS23 status in primary tumours and lymph node metastases according to MRPS23/CEP17 ratio, mean MRPS23 and amplification status

Mean MRPS23/tumour cell, primary tumours Marginal homogeneity test
 < 4  ≥ 4, < 6  ≥ 6 Total
Mean MRPS23/tumour cell, lymph nodes
 < 4 125 (97) 4 (40) 1 (20) 130 p = 0.637
 ≥ 4, < 6 3 (2) 5 (50) 2 (40) 10
 ≥ 6 1 (1) 1 (10) 2 (40) 4
 Total 129 10 5 144
MRPS23/CEP17 ratio, primary tumours
 < 2  ≥ 2 Total McNemar test
MRPS23/CEP17 ratio, lymph nodes
 < 2 130 (99) 3 (23) 133 p = 0.625
 ≥ 2 1 (1) 10 (76) 11
 Total 131 13 144
Amplification status, primary tumours
MRPS23 MRPS23+  Total McNemar test
Amplification status, lymph nodes
 MRPS23a 128 (98) 4 (29) 132 p = 0.688
 MRPS23+b 2 (2) 10 (71) 12
 Total 130 14 144

aMRPS23/CEP17 < 2 and mean MRPS23 < 6

bMRPS23/CEP17 ≥ 2 and/or mean MRPS23 ≥ 6