Table 5.

Associations between four SNPs, five haplotypes of CTSK, and serum P1NP in this study.

SNP	BETA	R2	P-valuea	haplotype	BETA	R2	P-valuea
rs12085336	0.020	8.368e-006	0.583	AGTT	0.072	0.0015	0.067
rs12746973	−0.219	2.346e-005	0.032	AGCC	−0.040	0.0004	0.265
rs4379678	−0.042	0.0004	0.385	AATC	−0.034	2.035e-005	0.483
rs10847	0.082	0.0015	0.187	TGTC	0.011	5.087e-006	0.737
				AGTC	−0.028	0.0002	0.571

Significant values (P < 0.05) are presented in bold. BETA regression coefficient, R² r-suqared regression coefficient,

^aadjusted for age and BMI.