Fig. 2. Environmental enrichment promotes oligodendrogenesis after perinatal brain injury.

a Experimental paradigm. BrdU was administered either from P11 to P15 (c) or P24−P28 (d). b Experimental groups. c Quantification of total EGFP + BrdU + CC1 + cells at P45, following BrdU injections immediately after HX (P11−P15) (n = 3 per group) (from left to right: ***p = 0.0006, ***p = 0.0008). d Quantification of total EGFP + BrdU + CC1 + cells at P45, following BrdU injections during EE (P24−P28) (NX, n = 5; NX-EE, n = 4; HX, n = 5; HX-EE, n = 4) (****p < 0.0001, ***p = 0.0008). Data expressed as mean ± SEM. One-way ANOVA followed by a Tukey’s post hoc test for multiple comparisons was used to compare differences between groups. Source data are provided as a Source Data file.