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. 2020 Feb 19;11:964. doi: 10.1038/s41467-020-14762-7

Fig. 4. Locomotor activity alone had no effects on OL maturation and did not improve functional recovery after perinatal brain injury.

Fig. 4

a Experimental paradigm. Activity control consisted of access to a running wheel. b Experimental groups. c Quantification of total EGFP + NG2 + OPCs at P22 (*p = 0.015) (NX, n = 3; NX Activity (NX-A), n = 3; NX-EE, n = 7; HX, n = 3; HX Activity (HX-A), n = 3; HX-EE, n = 6). d Quantification of total EGFP + CC1 + OLs at P45 (***p = 0.0002) (NX, n = 6; NX-A, n = 3; NX-EE, n = 6; HX, n = 6; HX-A, n = 3; HX-EE, n = 6). e Quantification of total EGFP + Olig2 + cells at P45 (****p < 0.0001)(NX, n = 7; NX-A, n = 3; NX-EE, n = 7; HX, n = 6; HX-A, n = 3; HX-EE, n = 7). f, g Quantification of foot slips on 2-cm inclined beam (**p = 0.006) (f) and 1-cm inclined beam (*p = 0.015) (g) at P45 (NX, n = 12; NX-A, n = 9; NX-EE, n = 12; HX, n = 10; HX-A, n = 8; HX-EE, n = 12). Data are expressed as mean ± SEM. One-way ANOVA followed by a Tukey’s post hoc test for multiple comparisons was used to compare differences between groups. Source data are provided as a Source Data file.