Table 1.

The comparison of reported methods for phenytoin detection.

Method	Sample	Linear range (µg/mL)	LOD (µg/mL)	Reference
1CMOS MEMS based MB biosensor	DMSO	5–100	4.06	This work
2MEMS based MCL biosensor	DI water/ serum	10–80	9.5	7
3SPR imaging	Human saliva	-	50  nM	21
4GC-TSD	Plasma	0.05–40	0.05–0.2	22
5HPLC	Serum /plasma	2.2–48.5	2.2	23
6FPIA	Serum	0–40	0.5	24,25

¹MB, membrane-bridge, ²MCL, microcantilever; ³SPR, surface plasmon resonance; ⁴GC-TSD, gas chromatography with thermionic specific detection; ⁵HPLC, high-performance liquid chromatography; ⁶FPIA, fluorescence polarization immunoassays.