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. 2020 Feb 19;10:6. doi: 10.1038/s41387-020-0109-6

Table 1.

Summary of studies reporting the effects of meal timings and dietary factors on glycaemic control.

Authors Year of publication Participants Main finding Ref. no.
Sakai et al.37 2018

Men and women

Type 2 diabetics

Late-night dinner independently associated with poor glycaemic control 37
Kajiyama et al.49 2018

Young women

Healthy

Late-night dinners increased postprandial hyperglycaemia

Consuming dinner dividedly ameliorate postprandial glucose levels

49
Imai et al.51 2017

Men and women

Type 2 diabetics

Late-night dinners increased postprandial hyperglycaemia 51
Van Cauter et al.46 1992

Men and women

Healthy

For identical mixed meals, total and 2-h AUC were 25–50% greater in the evening than in the morning 46
Jakubowicz et al.57 2013

Women

Overweight and obese metabolic syndrome (BMI: 32 kg/m2)

High-energy breakfast and reduced-energy dinner significantly reduces postprandial glycaemia in obese non-diabetic individuals 57
Jakubowicz et al.53 2015

Men and women

Type 2 diabetics

High-energy breakfast and reduced-energy dinner significantly lowered postprandial glycaemia 58
Jakubowicz et al.53 2015 Type 2 diabetics Skipping breakfast associated with a worsened glycaemic response after lunch and dinner in type 2 diabetics 53
Bo et al.56 2014

Men and women (45–64 years)

Exclusion: obesity and/or diabetes mellitus at baseline

Individuals in highest tertile of dinner, % daily caloric intake showed increased risk of incident type 2 diabetes 56
Bo et al.89 2015

Men and women

Healthy

Delayed and larger rises in glucose and insulin concentration after evening meals 89
Bandin et al.19 2015

Women

Healthy

Late eating of lunch showed increased postprandial glucose than early-eating 19
Tsuchida et al.64 2013

Women

Healthy

Late supper increased postprandial serum glucose profiles the following morning 64
Al-Naimi et al.50 2004

Men

Healthy

Meals and snacks eaten during simulated night shift work had higher postprandial glucose

Glucose tolerance impaired after first night-time meal, with no differences observed following second meal

50
Sato et al.48 2011

Men and women

Healthy

Increase in postprandial glucose after late evening meal which carried over to breakfast 48
Reutrakul et al.31 2014

Women

Type 2 diabetics

Breakfast skipping significantly associated with higher HbA1C values 31
Peter et al.52 2010

Men and women

Type 2 diabetics

Morning glucose excursions higher than in the evening

Decreased glucose tolerance for first and third meal of the day

52
Kobayashi et al.36 2014

Men

Healthy

Breakfast skipping, and big meals at lunch and dinner, had greater postprandial glucose, especially after dinner 36
Takahashi et al.90 2018

Men

Healthy

Higher postprandial glucose for evening meal than morning meal 90
Morgan et al.68 2012

Men and women

Healthy

Glucose levels higher with late consumption of high GI meals compared with low GI meals

Insulin sensitivity worsens with high-energy meals consumed in evening

68
Gibbs et al.69 2014

Men and women

Healthy

Postprandial glucose AUC showed effect with time of day after both low GI and high GI meals

Higher glycaemic responses in the evening for low GI meal

69
Leung et al.72 2019

Men and women

Healthy

Low GI meals at night contribute to higher glucose excursions and greater insulin levels compared with low GI meals in morning 72
Kessler et al.63 2017

Men

Non-obese (normal and impaired glucose, fasting tolerance)

Increased absorption of dietary cabohydrates late night resulting in a higher postprandial glucose profile the following morning 63
Davis et al.76 2019

Men and women

Healthy

High protein meal attenuates glucose excursions compared with a standard meal at night 76
Bonham et al.75 2019

Men

Healthy

Modifying night meal by reducing saturated fat and sugar improved postprandial glucose 75
Holmbäck et al.74 2002

Men

Healthy

High fat diet significant circadian pattern for plasma glucose compared with high carbohydrate diet 74
Gentilcore et al.77 2006 Type 2 diabetics Olive oil consumed 30 min before a potato meal attenuated postprandial rise in glucose 77
Sun et al.78 2017

Men

Healthy

Milk protein consumed before eating bread reduced GR 78
Sun et al.79 2015

Men

Healthy

Essence of chicken co-ingested with white bread reduced GR compared with white bread alone 79
Soong et al.80 2015

Men

Healthy

Essence of chicken co-ingested with white rice reduced GR compared with white rice alone 80
Takahashi et al.84 2019

Women

Healthy

Green tea consumption beneficial in the evening to reduce postprandial glucose concentrations by 3% lower than placebo 84
Sartorelli et al. 2019 Women Coffee and caffeine intake at lunch time inversely associated with the risk of diabetes 87
Lund et al.26 2001

Men and women

Shift workers

Observed abnormal metabolic responses for meals consumed at night during, due to insulin resistance 26
Hampton et al.27 1996

Men and women

Shift workers

Significant higher postprandial glucose and insulin responses at phase shift (body clock time 2230 h) 27