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. 2020 Feb 19;11:962. doi: 10.1038/s41467-020-14796-x

Fig. 3. High order chromatin organization in liver during chronic obesity.

Fig. 3

a, b Hi-C contact matrix depicting normalized contact frequencies in carbohydrate-rich diet (CD, Panel a) or lipid-rich diet (LD, Panel b) group at 50 and 10 kb bins (n = 2 per group). Examples at Chr1: 60–70 Mb. c Examples of TADs (Black triangle represents the TAD) and genes in Chr1: 60–70 Mb in LD and CD group. d Histograms of distribution of sizes of the TADs in CD and LD group. e Percentage of proximity TAD boundaries in CD and LD group.