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. 2020 Feb 19;11:962. doi: 10.1038/s41467-020-14796-x

Fig. 7. Hnf4α frequently co-binds with C/EBPα.

Fig. 7

a Overlap between Hnf4α and H3K27ac sites, regardless of diet conditions. b Motifs enriched in overlapping regions of Hnf4α and H3K27ac. c Overlap between Hnf4α and C/EBPα binding sites, regardless of diet. d The genome browser shot provides an example of colocalization of Hnf4α and C/EBPα binding at the Elovl6 locus. e GO analysis of Hnf4α and C/EBPα overlapping regions. f Heatmap of C/EBPα signal at diet-induced differentially bound regions. g, h GO analysis of C/EBPα differentially bound regions. i, j Motifs enriched at C/EBPα differentially bound regions. k Heatmap of Hnf4α and H3K27ac signal at C/EBPα differentially bound regions. l Metagene plot of Hnf4α signal at C/EBPα differentially bound regions. m Example of Hnf4α binding at a promoter interaction site as a bookmark for C/EBPα. n Metagene plot of C/EBPα at differentially bound regions with or without premarked Hnf4α. o Metagene plot of C/EBPα at differentially bound regions with or without premarked Hnf4α at promoter interactions. Significance (Mann–Whitney U test) is indicated in the figure.