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. 2020 Feb 13;9:1423. doi: 10.3389/fonc.2019.01423

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Copyright © 2020 Yan, Sun, Wu, Wu, Hu, Sun, Liu, Ma, Liu, Xiao, Liu and Ning.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Low PELP1 protein expression is a significant prognostic factor favoring good survival in gastric cancer (GC) patients. GC patients were grouped in 2 categories, those having high and low PELP1 gene expression based on the median. Box plots and data derived from ONCOMINE. Bioinformatics result was partly demonstrated by Kanplan-Meier survival analysis. (A) The survival curve analysis showed that there is a obviouly increase in the survival of the patients that have low PELP1 expression. (B) Box plots of gastric cancer grade showed that expression of PELP1 is relatively increased in higher grade. Values are the mean ± SEM. (C) The data from thirty-six GC tissues microarray revealed that patients with decreased PELP1 showed a longer OS (p < 0.05) (*p < 0.05, **p < 0.01, ***p < 0.001).