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. 2020 Feb 13;10:107. doi: 10.3389/fonc.2020.00107

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Copyright © 2020 Fu, Qie, Fu, Chen, Jin and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Global properties of miRNAs and pathways correlated with liver fibrosis. (A) Volcano plot of the DEMs (adjust P < 0.05 and |logFC| ≥ 2 were set as the cut-off criteria). (B) Heat map of the top 20 DEGs (top 10 up-regulated and 10 down-regulated genes). (C) Venn diagram of target genes predicted by miRDB, TargetScan, and miRtarbase. (D) KEGG pathway enrichment analysis of target genes of miR-20a-5p. The red lines represent gene count and the histogram represent –log₂ (P value).