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. 2020 Feb 19;10:2930. doi: 10.1038/s41598-020-60054-x

Table 2.

Demographic information of the study participants in each group.

Criteria Information lw-no lw-o hw-no hw-o P-value
Total WMHs Number of subjects 53 38 54 37 N/A
Age (years) 53.62 (7.81) 57.34 (5.87) 53.44 (7.10) 57.89 (6.24) 0.0028
Sex (male:female) 15:38 22:16 15:39 30:7 <0.001*
Waist circumference (cm) 82.55 (8.35) 95.74 (8.48) 81.11 (8.98) 98.68 (9.84) <0.001
Hip circumference (cm) 102.32 (6.97) 104.26 (8.47) 102.49 (8.21) 104.46 (6.93) 0.1546
Waist–hip ratio 0.81 (0.06) 0.92 (0.04) 0.79 (0.06) 0.94 (0.05) <0.001
Body mass index (kg/m2) 25.62 (3.57) 27.86 (4.25) 25.51 (3.73) 29.31 (3.88) <0.001
WMH volume (mm3) 1094.43 (498.13) 1204.87 (474.26) 5142.06 (3576.13) 5161.30 (3555.23) <0.001
Deep WMHs Number of subjects 54 37 53 38 N/A
Age (years) 54.35 (7.64) 57.41 (6.02) 52.70 (7.18) 57.82 (6.10) <0.001
Sex (male:female) 15:39 24:13 15:38 28:10 <0.001*
Waist circumference (cm) 82.07 (9.29) 97.14 (8.89) 81.56 (8.06) 97.24 (9.67) <0.001
Hip circumference (cm) 102.07 (7.55) 104.54 (8.64) 102.75 (7.67) 104.18 (6.77) 0.1526
Waist-hip ratio 0.80 (0.06) 0.93 (0.05) 0.79 (0.06) 0.93 (0.05) <0.001
Body mass index (kg/m2) 25.43 (3.87) 28.72 (4.47) 25.69 (3.41) 28.43 (3.78) <0.001
WMH volume (mm3) 54.11 (32.72) 45.22 (35.88) 731.28 (1002.09) 709.34 (860.22) <0.001
Periventricular WMHs Number of subjects 54 37 53 38 N/A
Age (years) 53.67 (7.80) 57.52 (6.10) 53.41 (7.14) 57.71 (6.02) 0.0039
Sex (male:female) 16:35 24:16 14:42 28:7 <0.001*
Waist circumference (cm) 82.49 (8.53) 95.88 (8.41) 81.21 (8.81) 98.69 (10.01) <0.001
Hip circumference (cm) 102.08 (6.88) 104.38 (8.28) 102.71 (8.22) 104.34 (7.09) 0.1423
Waist-hip ratio 0.81 (0.06) 0.92 (0.04) 0.79 (0.05) 0.94 (0.05) <0.001
Body mass index (kg/m2) 25.58 (3.54) 27.86 (4.12) 25.54 (3.75) 29.38 (4.01) <0.001
WMH volume (mm3) 914.47 (410.90) 1033.83 (431.33) 4417.11 (3270.81) 4764.91 (3256.12) <0.001

*Chi-square test. The lowest p-value was reported by comparing the four groups.

lw, low WMH burden; hw, high WMH burden; no, non-obese; o, obese; N/A, not available.