TABLE 3.
Differentially expressed proteins (DEPs) in ileum of 10-day-old broilers exposed to Citrobacter spp. (C2) in ovo.
UniProt ID | Proteins | Protein name | Fold change | p Value |
P05122 | CKB | Creatine kinase B | –1.250 | 0.002 |
P47836 | RPS4X | Ribosomal protein S4 X-linked | –1.600 | 0.002 |
Q2IAL7 | CATHL2 | Cathelicidin-2 | 4.500 | 0.003 |
P05122-5 | CPK-B | Creatine kinase B Isoform 4 | –10.000 | 0.006 |
P09652 | TUBB3 | Tubulin beta 3 class III | 2.900 | 0.006 |
Q9YGQ1 | EEF1B2 | Eukaryotic translation elongation factor 1 beta 2 | 1.800 | 0.008 |
Q5ZMU6 | PPP4R2 | Protein phosphatase 4 regulatory subunit 2 | ∞ | 0.016 |
P24802 | PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | 3.400 | 0.020 |
Q5ZHP5 | CHMP4B | Charged multivesicular body protein 4B | –1.600 | 0.021 |
Q5ZIW2 | CNOT10 | CCR4-NOT transcription complex subunit 10 | –5.000 | 0.028 |
Q5ZKA4 | EIF3J | Eukaryotic translation initiation factor 3 subunit J | 1.600 | 0.032 |
Q90615 | ITGA1 | Integrin subunit alpha 1 | 1.600 | 0.032 |
Q8UVD9 | KHSRP | Far upstream element-binding protein 2 | –1.420 | 0.034 |
P05083 | ASL | Argininosuccinate lyase | 2.300 | 0.035 |
Q5ZHN4 | RP2 | RP2, ARL3 GTPase activating protein | –3.300 | 0.037 |
Q5ZKC1 | EIF2A | Eukaryotic translation initiation factor 2A | ∞ | 0.039 |
P41125 | RPL13 | Ribosomal protein L13 | 1.700 | 0.041 |
Q5ZLR5 | UQCRFS1 | Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 1.600 | 0.044 |
P27731 | TTR | Transthyretin | 1.800 | 0.049 |
Q5ZLN1 | PGAM1 | Phosphoglycerate mutase 1 | –1.420 | 0.050 |
P23228 | HMGCS1 | 3-Hydroxy-3-methylglutaryl-CoA synthase 1 | –3.300 | 0.051 |
P08106 | HSPA2 | Heat shock protein family A (Hsp70) member 2 | –1.420 | 0.051 |
Q5ZK33 | LETM1 | Leucine zipper and EF-hand containing transmembrane protein 1 | 2.400 | 0.051 |
P49712 | ATP6V1B2 | ATPase H + transporting V1 subunit B2 | 1.600 | 0.052 |
Q5ZJU3 | ASNS | Asparagine synthetase (glutamine-hydrolyzing) | 1.700 | 0.053 |
P24797 | ATP1A2 | ATPase Na + /K + transporting subunit alpha 2 | –1.420 | 0.053 |
Q90629 | PRSS2 | Serine protease 2 | –2.500 | 0.053 |
O73885 | HSPA8 | Heat shock protein family A (Hsp70) member 8 | –1.420 | 0.054 |
P62846 | RPS15 | Ribosomal protein S15 | 2.000 | 0.060 |
P26990 | ARF6 | ADP ribosylation factor 6 | 2.600 | 0.061 |
Q90593 | HSPA5 | Heat shock protein family A (Hsp70) member 5 | –1.250 | 0.061 |
P30622 | CLIP1 | CAP-Gly domain containing linker protein 1 | ∞ | 0.062 |
P09540 | MYL4 | Myosin light chain 4 | 1.400 | 0.063 |
O75083 | WDR1 | WD repeat domain 1 | 3.000 | 0.063 |
P10184 | SPINK5 | Serine peptidase inhibitor, Kazal type 5 | 1.500 | 0.065 |
O59725 | mic60 | MICOS complex subunit Mic60 | 8.000 | 0.066 |
Q5ZL77 | RIC8A | RIC8 guanine nucleotide exchange factor A | ∞ | 0.066 |
P02675 | FGB | Fibrinogen beta chain | 1.800 | 0.068 |
Q90835 | EEF1A1 | Eukaryotic translation elongation factor 1 alpha 1 | 1.400 | 0.069 |
Q5ZLD7 | VPS53 | VPS53, GARP complex subunit | ∞ | 0.071 |
P12276 | FASN | Fatty acid synthase | 1.600 | 0.072 |
E1C2P3 | HSPA14 | Heat shock protein family A (Hsp70) member 14 | 3.200 | 0.072 |
Q5ZJJ2 | RPA1 | Replication protein A1 | –2.500 | 0.073 |
P02314 | HMGN2 | Non-histone chromosomal protein HMG-17 | –2.500 | 0.075 |
Q5ZLN0 | LRRC40 | Leucine rich repeat containing 40 | 2.000 | 0.076 |
O93256 | KRT19 | keratin 19 | 9.700 | 0.077 |
Q9YHT2 | SDHB | Succinate dehydrogenase complex iron sulfur subunit B | 1.900 | 0.078 |
P51890 | LUM | Lumican | –4.000 | 0.079 |
Q5ZLL5 | COQ5 | Coenzyme Q5, methyltransferase | 1.800 | 0.084 |
P04354 | CALB1 | Calbindin 1 | –1.600 | 0.086 |
Q5ZI72 | HNRNPDL | Heterogeneous nuclear ribonucleoprotein D like | 1.800 | 0.086 |
P02001 | HBAD | Hemoglobin subunit alpha-D | 1.800 | 0.088 |
P08251 | ATP1B1 | ATPase Na+/K+transporting subunit beta 1 | –2.500 | 0.089 |
P09102 | P4HB | Prolyl 4-hydroxylase subunit beta | –1.250 | 0.090 |
P12957 | Cald1 | Caldesmon 1 | –1.250 | 0.094 |
P68139 | ACTA1 | Actin, alpha 1, skeletal muscle | 3.200 | 0.096 |
P02612 | MYL9 | Myosin light chain 9 | 1.700 | 0.096 |
P26583 | HMGB2 | High mobility group box 2 | –2.500 | 0.097 |
P08940 | LECT2 | Leukocyte cell derived chemotaxin 2 | 5.100 | 0.097 |
Q5ZKQ5 | CASC4 | Cancer susceptibility 4 | –1.600 | 0.100 |
O13268 | PSMA7 | Proteasome subunit alpha 7 | –1.420 | 0.100 |
Q5ZHX1 | RAP1B | RAP1B, member of RAS oncogene family | 1.400 | 0.100 |
P27003 | S100A10 | S100 calcium binding protein A10 | ∞ | 0.100 |