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. 2019 Nov 6;34(2):e23064. doi: 10.1002/jcla.23064

Figure 3.

Figure 3

Location of two mutations in CSF3R. The T618I is related with JAK signaling, and the signal could be inhibited by JAK kinase inhibitor. The CSF3R truncation mutation (Y779*) is related with proliferation signaling via SFK‐TNK2, and this proliferation signaling is potentially inhibited by SFK‐TNK2 kinase inhibitor