Table 4.
Cox's regression model analysis of factors effecting DFS
| Items | Univariate Cox's regression | Multivariate Cox's regression | ||||||
|---|---|---|---|---|---|---|---|---|
| P value | HR | 95% CI | P value | HR | 95% CI | |||
| Lower | Higher | Lower | Higher | |||||
| AKIP1 expression (high vs low) | <.001 | 1.663 | 1.288 | 2.147 | .001 | 1.569 | 1.210 | 2.035 |
| Age (>60 y vs ≤60 y) | .191 | 1.178 | 0.922 | 1.506 | .110 | 1.235 | 0.953 | 1.599 |
| Gender (male vs female) | .896 | 0.979 | 0.712 | 1.346 | .988 | 1.003 | 0.719 | 1.397 |
| Tumor size (>5 cm vs ≤5 cm) | .099 | 1.231 | 0.962 | 1.575 | .102 | 0.740 | 0.516 | 1.061 |
| Lymph node metastasis (yes vs no) | <.001 | 1.752 | 1.357 | 2.262 | <.001 | 2.050 | 1.397 | 3.007 |
| TNM stage (III vs II/I) | .004 | 1.462 | 1.133 | 1.888 | .899 | 1.027 | 0.681 | 1.548 |
| Pathological differentiation (poor vs moderate/well) | .001 | 1.611 | 1.211 | 2.142 | <.001 | 1.732 | 1.281 | 2.341 |
Factors effecting DFS were determined by univariate and multivariate Cox's proportional hazards regression model analyses. P value < .05 was considered significant.
Abbreviations: AKIP1, A‐kinase‐interacting protein 1; DFS, disease‐free survival; TNM, tumor node metastasis.