Table 5.
Cox's regression model analysis of factors effecting OS
| Items | Univariate Cox's regression | Multivariate Cox's regression | ||||||
|---|---|---|---|---|---|---|---|---|
| P value | HR | 95% CI | P value | HR | 95% CI | |||
| Lower | Higher | Lower | Higher | |||||
| AKIP1 expression (high vs low) | <.001 | 1.933 | 1.435 | 2.604 | <.001 | 1.830 | 1.353 | 2.476 |
| Age (>60 y vs ≤60 y) | .637 | 1.068 | 0.813 | 1.402 | .781 | 1.042 | 0.779 | 1.395 |
| Gender (male vs female) | .682 | 0.930 | 0.657 | 1.317 | .796 | 0.954 | 0.665 | 1.367 |
| Tumor size (>5 cm vs ≤5 cm) | .002 | 1.521 | 1.160 | 1.994 | .865 | 0.969 | 0.673 | 1.394 |
| Lymph node metastasis (yes vs no) | <.001 | 2.300 | 1.744 | 3.034 | <.001 | 2.873 | 1.941 | 4.253 |
| TNM stage (III vs II/I) | .002 | 1.557 | 1.172 | 2.069 | .156 | 0.736 | 0.481 | 1.125 |
| Pathological differentiation (poor vs moderate/well) | .016 | 1.469 | 1.075 | 2.007 | .009 | 1.571 | 1.121 | 2.202 |
Factors effecting OS were determined by univariate and multivariate Cox's proportional hazards regression model analyses. P value < .05 was considered significant.
Abbreviations: AKIP1, A‐kinase‐interacting protein 1; OS, overall survival; TNM, tumor node metastasis.