Table 2.
Correlation of tumor circ‐LARP4 expression with clinical features
| Clinical features | Circ‐LARP4 low expression (n = 36)* | Circ‐LARP4 high expression (n = 36)* | P value |
|---|---|---|---|
| Age, No. (%) | |||
| <18 y | 19 (52.8) | 19 (52.8) | 1.000 |
| ≥18 y | 17 (47.2) | 17 (47.2) | |
| Gender, No. (%) | |||
| Female | 16 (44.4) | 14 (38.9) | .633 |
| Male | 20 (55.6) | 22 (61.1) | |
| Tumor location, No. (%) | |||
| Femur | 18 (50.0) | 20 (55.5) | .750 |
| Tibia | 14 (38.9) | 11 (30.6) | |
| Others | 4 (11.1) | 5 (13.9) | |
| WHO classification of sarcoma, No. (%) | |||
| Conventional: chondroblastic | 5 (13.9) | 5 (13.9) | .755 |
| Conventional: osteoblastic | 25 (69.5) | 22 (61.1) | |
| Conventional: other | 3 (8.3) | 6 (16.7) | |
| Telangiectatic | 3 (8.3) | 3 (8.3) | |
| Pathological fracture, No. (%) | |||
| No | 27 (75.0) | 31 (86.1) | .234 |
| Yes | 9 (25.0) | 5 (13.9) | |
| Enneking stage, No. (%) | |||
| IIA | 2 (5.6) | 9 (25.0) | .022 |
| IIB | 34 (94.4) | 27 (75.0) | |
| Surgery type, No. (%) | |||
| Amputation | 11 (30.6) | 10 (27.8) | .759 |
| Limb salvage | 25 (69.4) | 26 (72.2) | |
*
Low expression and high expression were categorized by the median value of circ‐LARP4 relative expression in tumor. Comparison was determined by the chi‐square test. WHO: World Health Organization.