Table 1.
Clinical characteristics of sepsis patients and HCs
| Items |
Sepsis patients (N = 150) |
HCs (N = 150) |
P value |
|---|---|---|---|
| Age (y), mean ± SD | 56.9 ± 10.3 | 55.1 ± 11.4 | 0.153 |
| Gender, No. (%) | |||
| Female | 52 (34.7) | 58 (38.7) | 0.472 |
| Male | 98 (65.3) | 92 (61.3) | |
| BMI (kg/m2), mean ± SD | 22.8 ± 4.8 | 22.3 ± 2.6 | 0.253 |
| Smoke, No. (%) | 58 (38.7) | – | – |
| Chronic comorbidities, No. (%) | |||
| COPD | 23 (15.3) | – | – |
| Cardiomyopathy | 49 (32.7) | – | – |
| Chronic kidney failure | 18 (12.0) | – | – |
| Cirrhosis | 28 (18.7) | – | – |
| Laboratory indexes, median (IQR) | |||
| Scr (mg/dL) | 1.7 (1.2‐2.4) | – | – |
| Albumin (g/L) | 27.2 (21.6‐36.8) | – | – |
| WBC (×109/L) | 14.0 (2.9‐28.1) | – | – |
| CRP (mg/L) | 98.5 (52.7‐128.8) | – | – |
| APACHE II score, mean ± SD | 16.3 ± 6.3 | – | – |
| SOFA score, mean ± SD | 7.3 ± 3.2 | – | – |
| Inflammatory cytokines, median (IQR) | |||
| TNF‐α (pg/mL) | 178.9 (120.0‐278.5) | – | – |
| IL‐6 (pg/mL) | 72.8 (42.2‐148.3) | – | – |
| IL‐17 (pg/mL) | 168.6 (76.8‐251.1) | – | – |
| IL‐23 (pg/mL) | 119.3 (56.9‐244.9) | – | – |
Comparison was determined by Student's t test or Chi‐square test.
Abbreviations: APACHE II score, acute pathologic and chronic health evaluation II score; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CRP, C‐reactive protein; HCs, healthy controls; IL, interleukin; IQR, interquartile range; Scr, serum creatinine; SD, standard deviation; SOFA score, sequential organ failure assessment score; TNF‐α, tumor necrosis factor‐α; WBC, white blood cell.