Table 1.
Clinical characteristics of AIS patients and controls
| Items | Controls (N = 320) | AIS patients (N = 320) | P value |
|---|---|---|---|
| Age (y), mean ± SD | 61.6 ± 9.1 | 62.6 ± 10.8 | .225 |
| Gender, No. (%) | |||
| Female | 65 (20.3) | 76 (23.8) | .294 |
| Male | 255 (79.7) | 244 (76.3) | |
| BMI (kg/m2), mean ± SD | 24.2 ± 2.8 | 24.7 ± 2.9 | .013 |
| Current smoke, No. (%) | |||
| No | 186 (58.1) | 179 (55.9) | .576 |
| Yes | 134 (41.9) | 141 (44.1) | |
| Common complications, No. (%) | |||
| Hypertension | 239 (74.7) | 274 (85.6) | .001 |
| Hyperlipidemia | 150 (46.9) | 156 (48.8) | .635 |
| Hyperuricemia | 101 (31.6) | 107 (33.4) | .613 |
| Diabetes mellitus | 60 (18.8) | 77 (24.1) | .101 |
| CKD | 30 (9.4) | 51 (15.9) | .013 |
| NIHSS score, mean ± SD | – | 8.4 ± 3.5 | – |
| Biochemical indexes, median (IQR) | – | – | |
| CRP (mg/L) | – | 41.5 (32.5‐57.2) | – |
| TNF‐α (pg/mL) | – | 41.2 (29.5‐57.8) | – |
| IL‐1β (pg/mL) | – | 89.8 (61.5‐148.4) | – |
| IL‐6 (pg/mL) | – | 7.9 (4.9‐10.7) | – |
| IL‐8 (pg/mL) | – | 71.0 (56.0‐93.1) | – |
| IL‐17 (pg/mL) | – | 79.0 (56.2‐113.6) | – |
| IL‐22 (pg/mL) | – | 148.9 (92.3‐201.7) | – |
Comparison was determined by Student's t test or the chi‐square test.
Abbreviations: AIS, acute ischemic stroke; BMI, body mass index; CKD, chronic kidney disease; CRP, C‐reactive protein; IL, interleukin; IQR, interquartile range; NIHSS, National Institute of Health stroke scale; SD, standard deviation; TNF‐α, tumor necrosis factor‐α.