Table 2.
Safety and tolerability assessments of participants after single or repeated administrations of red ginseng extract
>Factors | Test time | On day 1 | On day 15 |
---|---|---|---|
Systolic blood pressure | 0h (predose) | 121.5 ± 9.0 | 120.4 ± 9.1 |
2h | 125.1 ± 7.5 | 123.7 ± 6.9 | |
4h | 126.5 ± 9.4 | 123.1 ± 9.2 | |
8h | 121.8 ± 10.6 | 128.0 ± 9.4 | |
12h | 124.6 ± 8.1 | 126.6 ± 9.0 | |
Dystolic blood pressure | 0h (predose) | 78.9 ± 7.8 | 77.7 ± 8.8 |
2h | 81.2 ± 6.0 | 76.2 ± 5.3 | |
4h | 76.4 ± 8.5 | 76.5 ± 8.4 | |
8h | 71.3 ± 8.8 | 71.9 ± 7.1 | |
12h | 72.7 ± 8.9 | 71.5 ± 7.2 | |
Body temperature | 0h (predose) | 36.3 ± 0.1 | 36.3 ± 0.3 |
2h | 36.3 ± 0.2 | 36.4 ± 0.2 | |
4h | 36.5 ± 0.3 | 36.5 ± 0.2 | |
8h | 36.7 ± 0.2 | 36.7 ± 0.2 | |
12h | 36.7 ± 0.2 | 36.6 ± 0.2 | |
Alanine transaminase | 22.1 ± 9.8 | 17.0 ± 8.8 | |
Aspartate transaminase | 19.9 ± 8.7 | 21.6 ± 9.1 |
Data were expressed as mean ± SD of 15 participants
SD, standard deviation