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editorial
. 2020 Jan 26;12(1):1–7. doi: 10.4252/wjsc.v12.i1.1

Table 1.

Differences of mesenchymal stromal/stem cell niche, cell subpopulations, mesenchymal stromal/stem cell surface in vitro markers and multipotentiality between bone marrow and adipose tissue

Tissue MSC niche Cell subpopulations MSC in vitro surface markers Multipotentiality
Bone marrow Subendosteal and vascular Osteoblasts, Endothelial progenitor and mature cells, Macrophages, MSCs Positive: CD44, CD71, CD73, CD90, CD105, CD106, CD120a and Adipogenic, Chondrogenic, and Osteogenic. Pre-committed into osteogenic lineage.
Hematopoietic stem and progenitor cells, lymphocytes, megakaryocytes, erythrocytes, monocytes, neutrophils, basophils, eosinophils CD124
Negative: CD14, CD34 and CD45
Adipose tissue Vascular Adipocytes Positive: CD13, CD29, Adipogenic, Chondrogenic, and Osteogenic. Pre-committed into adipogenic lineage.
CD44, CD73, CD34, CD36, CD90 and CD105
SVF: Pre-adipocytes, endothelial progenitor and mature cells, macrophages, fibroblasts, MSCs Negative: CD31, CD45, CD235a and CD106

MSCs: Mesenchymal stromal/stem cells; SVF: Stromal-vascular fraction.