Table 3.

Pain outcomes stratified by follow-up duration and route of administration.

Cannabis vs Placebo by Route of Administration	Duration of Treatment	N of Comparisons	Weighted Mean Difference on 0-10 VAS Pain	Notes
Oral	1-14 days	3	−1.07 (−2.11 to −0.02)	Difference > 1 point
	2-8 weeks	10	−0.81 (−1.17 to −0.45)	Mild difference
	2-6 months	5	−0.48 (−0.91 to −0.05)	Mild difference
Oromucosal spray	1-14 days	11	−0.43 (−0.74 to −0.12)	Mild difference
	2-8 weeks	6	−0.46 (−1.04 to 0.11)	NS
	2-6 months	4	−0.39 (−0.93 to 0.15)	NS
Smoked	1-14 days	4	−0.42 (−0.92 to 0.09)	NS

Abbreviations: NS, not significant; VAS, visual analogue scale.