Fig. 1.

Methods to assess systolic and diastolic RV function using RV pressure waveforms. (a) Segmentation of the (1) RV pressure waveform using (2) pressure velocity (dP/dt) and (3) pressure acceleration (d²P/dt²) to define the isovolumetric contraction (IVC), ejection, isovolumetric relaxation (IVR), and filling regions. An RHC-derived MPI (Tei index) were derived using the ratio of the sum of the isovolumetric contraction (IVCT) and relaxation (IVRT) time to the RV ejection time (RVET) or RV MPI = (IVCT + IVRT) /RVET. (b) Single-beat method to estimate max isovolumetric pressure (Pmax) that was used in the estimation of the RV volume at zero pressure (V₀). (c) Assessment of the EDPVR when the RV volume at zero pressure was assumed to be zero (dashed line) or non-zero (V₀) (solid line) and derived as the intercept of the Ees with the volume axis.