Table 3.
Patients’ clinical characteristics for gene sequencing (n = 30)
| Variables | Sepsis-induced coagulopathy (n = 15) | Sepsis alone (n = 15) | P-value |
|---|---|---|---|
| Sex, F/M | 4/11 | 8/7 | P = 0.136a |
| Age, years | 62.60 ± 13.91 | 65.13 ± 20.40 | P = 0.694b |
| Cause of sepsis% | |||
| Pulmonary infection | 75% (9) | 25% (3) | P = 0.025a |
| Biliary system and pancreatic | 20% (1) | 80% (4) | P = 0.330a |
| Peritonitis | 40% (4) | 60% (6) | P = 0.439a |
| Urinary system | 50% (1) | 50% (1) | P = 1.000a |
| Cerebral | 0% (0) | 100% (1) | P = 1.000a |
| SOFA scores | 9.00 ± 4.33 | 6.21 ± 3.39 | P = 0.060b |
| APACHE II scores | 20.20 ± 8.19 | 15.59 ± 7.77 | P = 0.125b |
| PLT (×10^9/L) | 131.20 ± 87.78 | 156.87 ± 76.27 | P = 0.400b |
| D-dimer (mg/dL) | 13.94 ± 12.41 | 5.72 ± 5.49 | P = 0.026b |
| APTT (s) | 50.80 (39.70, 60.70) | 34.90 (33.40, 53.20) | P = 0.062c |
| PT (s) | 17.00 (14.20, 20.10) | 12.90 (12.50, 18.00) | P = 0.022c |
| PA% | 62.15 ± 19.45 | 70.51 ± 14.57 | P = 0.193b |
| INR | 1.51 ± 0.54 | 1.30 ± 0.29 | P = 0.197b |
| Fbg (mg/dL) | 294.60 (140.60, 340.80) | 310.30 (254.50, 533.40) | P = 0.262c |
| TT (s) | 21.50 (19.20, 114.45) | 23.00 (18.70, 282.90) | P = 0.787c |
| Cr (mmol/L) | 137.40 (74.05, 232.75) | 129.56 (77.80, 301.15) | P = 0.967c |
| BUN (mmol/L) | 11.32 ± 6.49 | 11.45 ± 6.38 | P = 0.959b |
aχ2 test, bStudent’s t test, cMann-Whitney U test, SOFA Sequential organ failure assessment, APACHE II Acute physiology and chronic health evaluation, PLT Platelet, APTT Activated partial thromboplastin time, PT Prothrombin time, PA Prothrombin activity, INR International normalized ratio, Fbg Fibrinogen, TT Thrombin Time, Cr Creatine, BUN Blood urea nitrogen