Figure 4:
Effects of soluble guanylate cyclase modulation on platelet cytosolic [Ca++] (Y axis).Soluble guanylate cyclase activator cinaciguat, but not the stimulator riociguat attenuates cytosolic calcium flux of platelets of patients with PE following thrombin or adenosine diphosphate (ADP) stimulation. *indicates P<0.05 by one way analysis of variance with Dunnett’s post-hoc with resting as the reference value.