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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Nitric Oxide. 2020 Jan 12;96:20–28. doi: 10.1016/j.niox.2020.01.004

Table 2.

Biomarkers of hemolysis

Haptoglobin Hemopexin Lactate dehydrogenase-1

Group Value T=0 hours T=24 hours T=0 hours T=24 hours T=0 hours T=24 hours

Pooled Pooled Placebo NO Pooled Pooled Placebo NO Pooled Pooled Placebo NO
PE median 29.0 46.5 31.2 49.5 21.2 22.7 23.3 22.0 92.6 90.8 93.0 67.7
 first
quartile 25.0 25.6 25.3 24.7 20.0 22.7 20.3 19.6 66.2 79.8 58.3 37.9
 third
quartile 59.0 55.5 59.0 52.3 24.7 25.2 26.7 24.7 114.0 116.0 114.0 116.1

Controls median 16.6 15.7 20.6 20.0 1.3 0.5
 first
quartile 18.5 4.6 18.5 18.4 0.0 0.0
 third
quartile 23.5 24.8 23.5 24.0 4.4 6.0

P value 0.07* 0.02 0.32** 0.8 0.4 0.28 0.01 0.03 0.09
*

P values comparing PE vs. Control from the Mann-Whitney U test;

**

P values comparing Placebo to NO from the Kruskal-Wallis repeated measures ANOVA