Table 2.
Various process parameters of drug layer in centrifugal granulator.
| S. No. | Processing parameter | Value |
|---|---|---|
| 1 | Rotational speed of plate | 200 rpm |
| 2 | Blower rate | 10 × 14 l/min |
| 3 | Air flow rate | 10 l/min |
| 4 | Spray air pressure | 0.5 MPa |
| 5 | Spray rate of solutiona | 4–7 g/min |
| 6 | Rotating rate of powder feederb | 0–15 rpm |
| 7 | Inlet temperature (°C) | 35 |
| 8 | Outlet temperature (°C) | 25 |
a
The spray rate was 4 g/min for the first 10 min, and gradually increased to 7 g/min until the end.
b
The rotating rate of feeder was 0 rpm for the first 10 min, and gradually increased to 15 rpm until the end.