Table 4.

Kinetic models of drug release and correlation coefficient.

Kinetic model	Equation	r
		Cymbalta®	Home-made
			Eudragit® L30D55	Aqoat® AS-LF	HPMCP (HP-55)
Zero-order model	$${\mathrm{Q}}_{\mathrm{t}}={\mathrm{k}}_0\mathrm{t}$$	0.8873	0.9273	0.8429	0.9337
First-order model	$$\ln \left({\mathrm{Q}}_0-{\mathrm{Q}}_{\mathrm{t}}\right)=-{\mathrm{k}}_1\mathrm{t}+\ln {\mathrm{Q}}_0$$	0.9750	0.9561	0.9741	0.9753
Higuchi diffusion model	$${\mathrm{Q}}_{\mathrm{t}}={\mathrm{k}}_{\mathrm{H}}{\mathrm{t}}^{\frac{1}{2}}$$	0.9234	0.8810	0.9293	0.9118
Ritger–Peppas model	$$\ln {\mathrm{Q}}_{\mathrm{t}}=\mathrm{n}\ln \mathrm{t}+{\mathrm{k}}_{\mathrm{R}}$$	0.9502	0.9414	0.9442	0.9599
Baker–Lonsdale model	$$\frac{3}{2}\left[1-{\left(1-{\mathrm{Q}}_{\mathrm{t}}\right)}^{\frac{2}{3}}\right]-{\mathrm{Q}}_{\mathrm{t}}={\mathrm{k}}_{\text{BL}}$$	0.8746	0.8347	0.8843	0.8597
Hixson–Crowell model	$${\left(1-{\mathrm{Q}}_{\mathrm{t}}\right)}^{\frac{1}{3}}=1-{\mathrm{k}}_{\text{HC}}$$	0.9762	0.9550	0.9761	0.9718
Weibull model	$${\mathrm{Q}}_{\mathrm{t}}=1-{\mathrm{e}}^{-\alpha {\mathrm{t}}^{\beta }}$$	0.9972	0.9909	0.9923	0.9957