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Quality safety evaluation of aFGF/SCOS thermo-sensitive hydrogel. (A) The appearance morphology of heart, liver, spleen, lung and kidney of mice in acute toxicity test (g, mean ± SD, n = 8). (B) Histopathological analysis of skin treated with aFGF thermo-sensitive hydrogel in biocompatibility test (H&E × 100): (a) Control; (b) Blank Hydrogel; (c) aFGF(2500 IU/g)/SCOS thermo-sensitive hydrogel; (d) aFGF (250 000 IU/g)/SCOS thermo-sensitive hydrogel.
