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. 2017 May 12;12(5):442–455. doi: 10.1016/j.ajps.2017.04.001

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Histological alterations in the liver and kidney at 21 d after administration of pure HP and Au-mPEG_(5000)-S-HP nanoparticles (H&E staining, 40×). Both (A₁) and (A₂) photomicrograph of liver and kidney section of control rat demonstrated normal cellular structure. Both (B₁) and (B₂) sections of liver and kidney of pure HP drug at 20 mg/kg b.wt show normal cellular architecture and both (C₁) and (C₂) section of liver and kidney of Au-mPEG_(5000)-S-HP nanoparticles drug at 0.5 ml depicted normal cellular architecture.