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. 2017 Jul 5;12(6):487–497. doi: 10.1016/j.ajps.2017.07.004

Table 4.

Ideal properties of drug for transdermal delivery.

Parameter Properties
Dose <10 mg/day
Half-life 10 h or less
Molecular weight <500 Dalton
Partition coefficient
Log P (octanol/water)
Between 1 and 3
Skin reaction Non irritating and non-sensitizing
Oral bioavailability Low