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. 2017 Oct 10;13(1):82–90. doi: 10.1016/j.ajps.2017.09.002

Table 2.

Main pharmacokinetic parameters of BDMC.

Compounds PK parameters BDMC raw material BDMC-PLGA-MS
BDMC V(c) (l/kg) 328.505 ± 42.259 1033.607 ± 386.348
T1/2 (min) 66.056 ± 10.755 305.707 ± 195.006
CL(s) (ml/min) 3.471 ± 0.261 2.656 ± 0.693
AUC (µg/min/ml) 4.893 ± 0.29 3.309 ± 0.183